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A small study of 12 healthy individuals found that those administered a drink containing green tea showed increased activity in the dorsolateral prefrontal cortex (DLPFC) of the brain compared to those who consumed a non-green tea drink, and the larger the dose of green tea, the greater the activation. The DLPFC mediates working memory processing in the human brain. (Neural effects of green tea extract on dorsolateral prefrontal cortex. European Journal of Clinical Nutrition (2012) 66, 1187