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A review from China explains that electro-acupuncture (EA) treatment following ischaemic brain injury may produce neuroregenerative or neuroprotective effects via a series of molecular signalling pathways. The authors summarise the mechanisms by which EA may act on ischaemic stroke; via suppressing apoptosis, alleviating glutamate excitotoxicity, enhancing cerebral blood flow and growth factor production, regulating oxidative injury, maintaining blood-brain barrier integrity and generating cerebral ischemic tolerance. They explain the potential beneficial influence of acupuncture on apoptosis related-factors, inflammatory mediators, autophagy-related factors, growth factors, transcription factors and cannabinoid CB1 receptors.

Mechanisms Involved in the Neuroprotection of Electroacupuncture Therapy for Ischemic Stroke. Front Neurosci. 2018 Dec 11;12:929.

 

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