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KUDZU CAUSES AVERSION TO ALCOHOL
A synthetic derivative of the kudzu vine [Ge Gen (Puerariae Radix)] has been shown to reduce drinking and prevent relapse in a rat model of alcoholism. Kudzu contains daidzin, a substance which causes aversion to drinking alcohol. Daidzin inhibits the enzyme aldehyde dehydrogenase 2 (ALDH-2), which metabolises alcohol into acetaldehyde. Decreased drinking due to ALDH-2 inhibition is attributed to ...
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